CHICAGO (AP) - Airlines are pre-emptively canceling hundreds of flights at Chicago's two airports as a powerful storm takes aim at parts of the Midwest and Great Lakes region.

As of Wednesday morning, nearly 900 flights in and out of Chicago were cancelled. That's according to the aviation tracking website FlightAware.com. The vast majority of the cancellations were at O'Hare International Airport, which serves as a major hub for both United and American Airlines.

Other airports in the path of the storm, including in St. Louis and Detroit, showed no significant disruption.

Forecasters say the storm could dump 12 to 18 inches of snow along Indiana's coast of Lake Michigan. Motorists are being warned of zero visibility at times on roadways.

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